What benefits for Esmya?
For women with fibroids, this PEARL IV study of the Esmya drug from Gedeon Richter Lab could make a real difference. It shows that after 12 weeks of intermittent * treatment with Esmya 5 mg, bleeding, one of the most painful effects of fibroids, has reduced in at least 93% of women .
The volume of fibroids is also concerned since in 67% of women, the 3 largest fibroids have seen their size decrease. And for some, the fibroma (s) have disappeared altogether. "As if the drug had killed the fibroid," said Professor Jacques Jacques Jacques, gynecologist and coordinator of the Pearl IV study. So, if some women took Esmya, preoperatively, to arrive in better conditions to the intervention (less anemic and with a smaller fibroid and therefore more easily operable), "it happened," said Professor Don, that the surgical intervention becomes useless ".
The end of the hormones to treat the fibroid?
End of excessive bleeding, decrease in the size or disappearance of the fibroid, the benefits of the molecule of Esmya, ulipristal acetate, do not stop there:
- unlike the hormonal drugs traditionally used so far, the GnRH agonists (gonadotrophin-releasing hormone), Esmya does not involve a state of menopause .
- Esmya is also effective in 7 days (against 3 weeks for other drugs).
- Finally, at the end of treatment, the fibroid does not regross , which is the case with GnRH agonists.
Note: in 3% of women, the drug Esmya had none of the expected benefits.
* cycles of 3 months interrupted by two months of break.